1Įxperience in Known or Suspected Cyanide Poisoning VictimsA total of 245 patients received hydroxocobalamin treatment in these studies. However, 4 open-label, uncontrolled clinical studies were conducted in known or suspected cyanide poisoning victims.

Hydroxocobalamin, the active ingredient in CYANOKIT, has been used in France since the 1980s, was formally licensed there in 1996, and was approved in the United States in 2006 to treat known or suspected cyanide poisoning 6,7Ĭlinical ExperienceRandomized clinical trials in humans are not possible due to ethical considerations, therefore evidence in controlled trials of the effectiveness of hydroxocobalamin for the treatment of cyanide poisoning was obtained primarily from studies in animals.CYANOKIT can be used to treat multiple sources of cyanide poisoning, including smoke inhalation and ingestion 1.If clinical suspicion of cyanide poisoning is high, CYANOKIT should be administered without delay 1 CYANOKIT for intravenous infusion is indicated for the treatment of known or suspected cyanide poisoning.If cyanide poisoning is known or suspected, treat with CYANOKIT-an FDA-approved treatment option for cyanide poisoning. 1Signs and symptoms of acute systemic cyanide poisoning may develop rapidly, depending on the route and extent of cyanide exposure.

1 The expert advice of a regional poison control center may be obtained by calling 1-80. Airway, ventilatory and circulatory support, oxygen administration, and management of seizures should not be delayed to administer CYANOKIT. Comprehensive treatment of acute cyanide intoxication requires support of vital functions.

Cyanide antidote kit contains